MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis

• Glavni autori: Anying Wang (Autor), Naixia Hu (Autor), Yefeng Zhang (Autor), Yuanzhen Chen (Autor), Changhui Su (Autor), Yao Lv (Autor), Yong Shen (Autor)
• Format: Knjiga
• Izdano: BMC, 2019-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Background This study aimed to investigate the role of long non-coding RNA (lncRNA) maternally expressed 3 (MEG3) and related molecular mechanisms, in osteoarthritis (OA). Methods Cartilage tissues of OA patients and healthy volunteers were isolated and cultured. After transfection with the...