Establishment and Characterization of a Novel Rat Model of Mechanical Low Back Pain Using Behavioral, Pharmacologic and Histologic Methods

• Main Authors: Arjun Muralidharan (Author), Thomas S. W. Park (Author), John T. Mackie (Author), Luiz G. S. Gimenez (Author), Andy Kuo (Author), Janet R. Nicholson (Author), Laura Corradini (Author), Maree T. Smith (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic low back pain (LBP), the leading cause of disability globally, is notoriously difficult to treat. Most rodent models of LBP mimic lumbar radicular pain rather than mechanical LBP. Here, we describe establishment of a new rat model of mechanical LBP that is devoid of a neuropathic component....