Preliminary Studies on Validation of Calu-3 Cell Line as a Model for Screening Respiratory Mucosa Irritation and Toxicity

• Auteurs principaux: Chibueze Ihekwereme (Auteur), Charles Esimone (Auteur), Di Shao (Auteur), Remigius U. Agu (Auteur)
• Format: Livre
• Publié: MDPI AG, 2014-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

There is need to develop reproducible methods and experimental models for screening mucosal irritation and toxicity for drugs and pharmaceutical excipients. The aim of this study was to validate Calu-3 cell line as a model for screening respiratory irritation and toxicity of drugs and excipients. Ei...