Transcriptome analysis to explore the mechanism of downregulated TNIK influencing the effect of risperidone

• Main Authors: Ruixue Yuan (Author), Yaojing Li (Author), Xiangyi Li (Author), Yingmei Fu (Author), Ailing Ning (Author), Dongxiang Wang (Author), Ran Zhang (Author), Shunying Yu (Author), Qingqing Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundRisperidone is one of the most reliable and effective antipsychotics for schizophrenia treatment. However, the mechanism of action of risperidone is not yet fully understood. Traf2 and Nck-interacting protein kinase (TNIK), a schizophrenia susceptibility gene, is associated with risperidon...