Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice

• Main Authors: Sarah Giese (Author), Hamid Hossain (Author), Melanie Markmann (Author), Trinad Chakraborty (Author), Svetlin Tchatalbachev (Author), Florian Guillou (Author), Martin Bergmann (Author), Klaus Failing (Author), Karola Weider (Author), Ralph Brehm (Author)
• Format: Book
• Published: The Company of Biologists, 2012-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY A significant decline in human male reproductive function has been reported for the past 20 years but the molecular mechanisms remain poorly understood. However, recent studies showed that the gap junction protein connexin-43 (CX43; also known as GJA1) might be involved. CX43 is the predomin...