Glucocorticoid-Induced Leucine Zipper: A Novel Anti-inflammatory Molecule

• Main Authors: Oxana Bereshchenko (Author), Graziella Migliorati (Author), Stefano Bruscoli (Author), Carlo Riccardi (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Glucocorticoids (GCs) are the most commonly used drugs for treatment of autoimmune and inflammatory diseases. Their efficacy is due to their ability to bind cytoplasmic receptors (glucocorticoid receptors, GR) and other cytoplasmic proteins, thus regulating gene expression. Although GCs are potent l...