Pullulan microbeads/Si-HPMC hydrogel injectable system for the sustained delivery of GDF-5 and TGF-β1: new insight into intervertebral disc regenerative medicine

• Main Authors: Nina Henry (Author), Johann Clouet (Author), Audrey Fragale (Author), Louise Griveau (Author), Claire Chédeville (Author), Joëlle Véziers (Author), Pierre Weiss (Author), Jean Le Bideau (Author), Jérôme Guicheux (Author), Catherine Le Visage (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Discogenic low back pain is considered a major health concern and no etiological treatments are today available to tackle this disease. To clinically address this issue at early stages, there is a rising interest in the stimulation of local cells by in situ injection of growth factors targeting inte...