IMMUNOMETABOLIC REGULATION OF BACTERIAL INFECTION, BIOFILMS, AND ANTIBIOTIC SUSCEPTIBILITY

• Main Authors: Ying-Tsun Chen (Author), Gaurav Kumar Lohia (Author), Samantha Chen (Author), Sebastián A. Riquelme (Author)
• פורמט: ספר
• יצא לאור: Karger Publishers, 2024-02-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

BACKGROUND: Upon infection, mucosal tissues activate a brisk inflammatory response to clear the pathogen: i.e., resistance to disease. Resistance to disease is orchestrated by tissue-resident macrophages, which undergo profound metabolic reprogramming after sensing the pathogen. These metabolically...