Hypoxia-Response Plasmid Vector Producing bcl-2 shRNA Enhances the Apoptotic Cell Death of Mouse Rectum Carcinoma

• 主要な著者: Takashi Fujioka (著者), Naoya Matsunaga (著者), Hiroyuki Okazaki (著者), Satoru Koyanagi (著者), Shigehiro Ohdo (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2010-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Hypoxia-induced gene expression frequently occurs in malignant solid tumors because they often have hypoxic areas in which circulation is compromised due to structurally disorganized blood vessels. Hypoxia-response elements (HREs) are responsible for activating gene transcription in response to hypo...