Administration of PDE4 Inhibitors Suppressed the Pannus-Like Inflammation by Inhibition of Cytokine Production by Macrophages and Synovial Fibroblast Proliferation

A marked proliferation of synovial fibroblasts in joints leads to pannus formation in rheumatoid arthritis (RA). Various kinds of cytokines are produced in the pannus. The purpose of this study is to elucidate the effects of phosphodiesterase 4 (PDE4) inhibitors in a new animal model for the evaluat...

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Main Authors: Katsuya Kobayashi (Author), Toshio Suda (Author), Haruhiko Manabe (Author), Ichiro Miki (Author)
Format: Book
Published: Hindawi Limited, 2007-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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