Expression and Functional Characterization of Choline Transporter in Human Keratinocytes

• Main Authors: Yoshihiro Uchida (Author), Masato Inazu (Author), Hiroshi Takeda (Author), Tomoko Yamada (Author), Hirohisa Tajima (Author), Teruhiko Matsumiya (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Choline is essential for synthesis of the major membrane phospholipid phosphatidylcholine. Moreover, it serves as a precursor for synthesis of the neurotransmitter acetylcholine (ACh). Keratinocytes of the epidermis synthesize and release ACh. The uptake of choline is the rate-limiting step in both...