Study of patterns of inheritance of premature ovarian failure syndrome carrying maternal and paternal premutations

• Main Authors: Artur Beke (Author), Henriett Piko (Author), Iren Haltrich (Author), Veronika Karcagi (Author), Janos Rigo (Author), Maria Judit Molnar (Author), György Fekete (Author)
• Format: Book
• Published: BMC, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Premature ovarian failure / primary ovarian insufficiency (POF/POI) associated with the mutations of the FMR1 (Fragile-X Mental Retardation 1) gene belongs to the group of the so-called trinucleotide expansion diseases. Our aim was to analyse the relationship between the paternal...