Allosteric modulation of adenosine A1 and cannabinoid 1 receptor signaling by G‐peptides

• Main Authors: Anja M. Touma (Author), Rabia U. Malik (Author), Tejas Gupte (Author), Sivaraj Sivaramakrishnan (Author)
• Formato: Livro
• Publicado em: Wiley, 2020-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract While allosteric modulation of GPCR signaling has gained prominence to address the need for receptor specificity, efforts have mainly focused on allosteric sites adjacent to the orthosteric ligand‐binding pocket and lipophilic molecules that target transmembrane helices. In this study, we e...