Comprehensive in vitro pro‐arrhythmic assays demonstrate that omecamtiv mecarbil has low pro‐arrhythmic risk

Abstract Omecamtiv mecarbil (OM) is a myosin activator (myotrope), developed as a potential therapeutic agent for heart failure with reduced ejection fraction. To characterize the potential pro‐arrhythmic risk of this novel sarcomere activator, we evaluated OM in a series of International Conference...

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Main Authors: Yusheng Qu (Author), BaoXi Gao (Author), Ziva Arimura (Author), Mei Fang (Author), Hugo M. Vargas (Author)
Format: Book
Published: Wiley, 2021-07-01T00:00:00Z.
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