Pharmacokinetics of anticoagulant edoxaban in overdose in a Japanese patient transported to hospital

• Main Authors: Koichiro Adachi (Author), Jumpei Tuchiya (Author), Satoru Beppu (Author), Kei Nishiyama (Author), Makiko Shimizu (Author), Hiroshi Yamazaki (Author)
• Format: Book
• Published: BMC, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The anticoagulant edoxaban is used clinically at doses of 30-60 mg/day; however, we experienced a patient who had taken an overdose of edoxaban of 750 mg. We investigated the pharmacokinetics of edoxaban in this patient by using liquid chromatography-tandem spectrometry to estima...