Formulation and Characterization of Epalrestat-Loaded Polysorbate 60 Cationic Niosomes for Ocular Delivery

• Auteurs principaux: Axel Kattar (Auteur), Ana Quelle-Regaldie (Auteur), Laura Sánchez (Auteur), Angel Concheiro (Auteur), Carmen Alvarez-Lorenzo (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The aim of this work was to develop niosomes for the ocular delivery of epalrestat, a drug that inhibits the polyol pathway and protects diabetic eyes from damage linked to sorbitol production and accumulation. Cationic niosomes were made using polysorbate 60, cholesterol, and 1,2-di-O-octadecenyl-3...