Formulation and Characterization of Epalrestat-Loaded Polysorbate 60 Cationic Niosomes for Ocular Delivery

• Główni autorzy: Axel Kattar (Autor), Ana Quelle-Regaldie (Autor), Laura Sánchez (Autor), Angel Concheiro (Autor), Carmen Alvarez-Lorenzo (Autor)
• Format: Książka
• Wydane: MDPI AG, 2023-04-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The aim of this work was to develop niosomes for the ocular delivery of epalrestat, a drug that inhibits the polyol pathway and protects diabetic eyes from damage linked to sorbitol production and accumulation. Cationic niosomes were made using polysorbate 60, cholesterol, and 1,2-di-O-octadecenyl-3...