Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study

• Main Authors: Wernimont Susan M (Author), Clark Andrew G (Author), Stover Patrick J (Author), Wells Martin T (Author), Litonjua Augusto A (Author), Weiss Scott T (Author), Gaziano J Michael (Author), Tucker Katherine L (Author), Baccarelli Andrea (Author), Schwartz Joel (Author), Bollati Valentina (Author), Cassano Patricia A (Author)
• Formato: Livro
• Publicado em: BMC, 2011-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Sequence variants in genes functioning in folate-mediated one-carbon metabolism are hypothesized to lead to changes in levels of homocysteine and DNA methylation, which, in turn, are associated with risk of cardiovascular disease.<...