Elevated plasma syndecan-1 as glycocalyx injury marker predicts unfavorable outcomes after rt-PA intravenous thrombolysis in acute ischemic stroke

• Main Authors: Fangfang Zhao (Author), Rongliang Wang (Author), Yuyou Huang (Author), Lingzhi Li (Author), Liyuan Zhong (Author), Yue Hu (Author), Ziping Han (Author), Junfen Fan (Author), Ping Liu (Author), Yangmin Zheng (Author), Yumin Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: We aimed to examine the prognostic value of syndecan-1 as a marker of glycocalyx injury in patients with acute ischemic stroke (AIS) receiving rt-PA intravenous thrombolysis.Methods: The study included 108 patients with AIS treated with rt-PA intravenous thrombolysis and 47 healthy controls...