Acceleration of the DNA methylation clock among lynch syndrome-associated mutation carriers

• Main Authors: Marta Cuadros (Author), Carlos Cano (Author), Sonia Garcia-Rodriguez (Author), José Luis Martín (Author), Antonio Poyatos-Andujar (Author), Francisco Ruiz-Cabello (Author), Susana Pedrinaci (Author), Gema Durán (Author), Manuel Benavides (Author), María Dolores Bautista-Ojeda (Author), Teresa Pereda (Author), Maria Soledad Benitez-Cantos (Author), Pedro Medina (Author), Armando Blanco (Author), Antonio Gonzalez (Author), Paul Lizardi (Author)
• Format: Book
• Published: BMC, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background DNA methylation (DNAm) age metrics have been widely accepted as an epigenetic biomarker for biological aging and disease. The purpose of this study is to assess whether or not individuals carrying Lynch Syndrome-associated mutations are affected in their rate of biological aging,...