Acceleration of the DNA methylation clock among lynch syndrome-associated mutation carriers

• Главные авторы: Marta Cuadros (Автор), Carlos Cano (Автор), Sonia Garcia-Rodriguez (Автор), José Luis Martín (Автор), Antonio Poyatos-Andujar (Автор), Francisco Ruiz-Cabello (Автор), Susana Pedrinaci (Автор), Gema Durán (Автор), Manuel Benavides (Автор), María Dolores Bautista-Ojeda (Автор), Teresa Pereda (Автор), Maria Soledad Benitez-Cantos (Автор), Pedro Medina (Автор), Armando Blanco (Автор), Antonio Gonzalez (Автор), Paul Lizardi (Автор)
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• Опубликовано: BMC, 2022-03-01T00:00:00Z.
• Предметы: article
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Abstract Background DNA methylation (DNAm) age metrics have been widely accepted as an epigenetic biomarker for biological aging and disease. The purpose of this study is to assess whether or not individuals carrying Lynch Syndrome-associated mutations are affected in their rate of biological aging,...