Doxorubicin-Conjugated Innovative 16-mer DNA Aptamer-Based Annexin A1 Targeted Anti-Cancer Drug Delivery

• Main Authors: Rohit Bavi (Author), Zhang Hang (Author), Parikshit Banerjee (Author), Md Aquib (Author), Mahendra Jadhao (Author), Niraj Rane (Author), Sneha Bavi (Author), Raghunath Bhosale (Author), Kisan Kodam (Author), Byong-Hun Jeon (Author), Yueqing Gu (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aptamers are small, functional single-stranded DNA or RNA oligonucleotides that bind to their targets with high affinity and specificity. Experimentally, aptamers are selected by the systematic evolution of ligands by exponential enrichment (SELEX) method. Here, we have used rational drug designing...