Irisin Exerts Neuroprotective Effects on Cultured Neurons by Regulating Astrocytes

• Main Authors: Kexin Wang (Author), Hongyan Li (Author), Hongxing Wang (Author), Jun-hui Wang (Author), Feng Song (Author), Yu Sun (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neurons suffer detrimental effects from β-amyloid toxicity in Alzheimer's disease. The exercise hormone, irisin, is found to induce a neuroprotective gene program and facilitates the beneficial effects on cognitive function. But no effort is made to test its direct protective effects on neurons...