Validation and interpretation of Pan-TRK immunohistochemistry: a practical approach and challenges with interpretation

Abstract Objectives Actionable, solid tumor activating neurotrophic receptor tyrosine kinase (NTRK) fusions are best detected via nucleic acid-based assays, while Pan-TRK immunohistochemistry (IHC) serves as a reasonable screening modality. We describe a practical and cost-effective approach to vali...

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Main Authors: Cansu Karakas (Author), Ellen J. Giampoli (Author), Tanzy Love (Author), David G. Hicks (Author), Moises J. Velez (Author)
Format: Book
Published: BMC, 2024-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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