Synthesis, Characterization and Preliminary Pharmacological Evaluation of Triazolothiadiazoles Derived from some NSAIDs and Thiocarbohydrazide

• Main Authors: Manar Serhan Ahmed (Author), Hayder Jafer Essa (Author), Ayad Kareem Khan (Author)
• Format: Book
• Published: College of Pharmacy / Mustansiriyah University, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The synthesis of new NSAIDs with improved efficacy and selectivity towards COX2, which encouraged by the various biological activities of 1,2,4-triazoles and 1,3,4-thiadiazoles. In this experiment, the production of 1,2,4-triazolothiadiazoles derivatives from Ibuprofen, Naproxen and Indomethacin. We...