The effect of montelukast, a leukotriene receptor antagonist, on the acetic acid-induced model of colitis in rats: Involvement of NO-cGMP-KATP channels pathway

• Hlavní autoři: Behnam Ghorbanzadeh (Autor), Mohammad Amin Behmanesh (Autor), Roya Mahmoudinejad (Autor), Mehdi Zamaniyan (Autor), Shadi Ekhtiar (Autor), Yousef Paridar (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Témata: article
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Inflammatory bowel disease is a chronic autoimmune disorder that may involve entire gastrointestinal tract. The leukotrienes have a role as mediators in the pathophysiology of colitis. Here, we investigated the effect of a leukotriene receptor antagonist, montelukast, and also the role of the NO-cGM...