Fixation alters the physical properties of tumor tissue that regulate nanomedicine transport

• Main Authors: John D. Martin (Author), Fotios Mpekris (Author), Vikash P. Chauhan (Author), Margaret R. Martin (Author), Megan E. Walsh (Author), Matthew D. Stuber (Author), Donald M. McDonald (Author), Fan Yuan (Author), Triantafyllos Stylianopoulos (Author), Rakesh K. Jain (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To have the desired therapeutic effect, nanomedicines and macromolecular medications must move from the site of injection to the site of action, without having adverse effects. Transvascular transport is a critical step of this navigation, as exemplified by the Enhanced Permeability and Retention (E...