Intracellular acidity impedes KCa3.1 activation by Riluzole and SKA-31

Background:The unique microenvironment in tumors inhibits the normal functioning of tumor-infiltrating lymphocytes, leading to immune evasion and cancer progression. Over-activation of KCa3.1 using positive modulators has been proposed to rescue the anti-tumor response. One of the key characteristic...

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Bibliographic Details
Main Authors: Marco Cozzolino (Author), Gyorgy Panyi (Author)
Format: Book
Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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