Intracellular acidity impedes KCa3.1 activation by Riluzole and SKA-31
Background:The unique microenvironment in tumors inhibits the normal functioning of tumor-infiltrating lymphocytes, leading to immune evasion and cancer progression. Over-activation of KCa3.1 using positive modulators has been proposed to rescue the anti-tumor response. One of the key characteristic...
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Frontiers Media S.A.,
2024-04-01T00:00:00Z.
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