Population pharmacokinetics of atacicept in systemic lupus erythematosus: An analysis of three clinical trials

• Hlavní autoři: Maria Pitsiu (Autor), Özkan Yalkinoglu (Autor), Colm Farrell (Autor), Pascal Girard (Autor), Cristina Vazquez‐Mateo (Autor), Orestis Papasouliotis (Autor)
• Médium: Kniha
• Vydáno: Wiley, 2023-08-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract B cell stimulating factor (BLyS) and a proliferation‐inducing ligand (APRIL) are targets for novel treatments in patients with systemic lupus erythematosus (SLE). Atacicept is a recombinant, soluble fusion protein that blocks BLyS and APRIL activity. This study characterized the pharmacokin...