Effective improvement of the neuroprotective activity after spinal cord injury by synergistic effect of glucocorticoid with biodegradable amphipathic nanomicelles

• Main Authors: YueLong Wang (Author), Min Wu (Author), Lei Gu (Author), XiaoLing Li (Author), Jun He (Author), LiangXue Zhou (Author), Aiping Tong (Author), Juan Shi (Author), HongYan Zhu (Author), JianGuo Xu (Author), Gang Guo (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dexamethasone acetate (DA) produces neuroprotective effects by inhibiting lipid peroxidation and inflammation by reducing cytokine release and expression. However, its clinical application is limited by its hydrophobicity, low biocompatibility and numerous side effects when using large dosage. There...