Gadd45b is required in part for the anti-obesity effect of constitutive androstane receptor (CAR)

• Autori principali: Xinran Cai (Autore), Ye Feng (Autore), Meishu Xu (Autore), Chaohui Yu (Autore), Wen Xie (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2021-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Crosstalk between xenobiotic metabolism and energy metabolism in the liver has provided a potential opportunity to target xenobiotic receptors to treat metabolic diseases. Activation of constitutive androstane receptor (CAR), a xenobiotic-sensing nuclear receptor, has been shown to inhibit obesity,...