Role of PRDM1 in Tumor Immunity and Drug Response: A Pan-Cancer Analysis

• Главные авторы: Lujun Shen (Автор), Qifeng Chen (Автор), Changsheng Yang (Автор), Ying Wu (Автор), Hui Yuan (Автор), Shuanggang Chen (Автор), Shunling Ou (Автор), Yiquan Jiang (Автор), Tao Huang (Автор), Liangru Ke (Автор), Jinqing Mo (Автор), Ziqing Feng (Автор), Penghui Zhou (Автор), Weijun Fan (Автор)
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• Опубликовано: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Предметы: article
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Background: PR domain zinc finger protein 1 (PRDM1) is a regulator of both B cell and T cell differentiation and plays a critical role in immunosuppression. Its role in tumor immunity and correlation with drug response remain unknown.Methods: This work comprehensively analyzed the transcriptional ex...