Role of PRDM1 in Tumor Immunity and Drug Response: A Pan-Cancer Analysis

• Main Authors: Lujun Shen (Author), Qifeng Chen (Author), Changsheng Yang (Author), Ying Wu (Author), Hui Yuan (Author), Shuanggang Chen (Author), Shunling Ou (Author), Yiquan Jiang (Author), Tao Huang (Author), Liangru Ke (Author), Jinqing Mo (Author), Ziqing Feng (Author), Penghui Zhou (Author), Weijun Fan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: PR domain zinc finger protein 1 (PRDM1) is a regulator of both B cell and T cell differentiation and plays a critical role in immunosuppression. Its role in tumor immunity and correlation with drug response remain unknown.Methods: This work comprehensively analyzed the transcriptional ex...