Testing the Protective Effects of Sulfobutylether-Βeta-Cyclodextrin (SBECD) and Sugammadex against Chlorpromazine-Induced Acute Toxicity in SH-SY5Y Cell Line and in NMRI Mice

• Main Authors: Eszter Fliszár-Nyúl (Author), Rita Csepregi (Author), Gábor Benkovics (Author), Lajos Szente (Author), Miklós Poór (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2022-09-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Chlorpromazine (CPZ) is an antipsychotic drug which can cause several adverse effects and drug poisoning. Recent studies demonstrated that CPZ forms highly stable complexes with certain cyclodextrins (CDs) such as sulfobutylether-β-CD (SBECD) and sugammadex (SGD). Since there is no available antidot...