Taste, a new incentive to switch to (R)-praziquantel in schistosomiasis treatment.

• Main Authors: Thorsten Meyer (Author), Harald Sekljic (Author), Stefan Fuchs (Author), Heiko Bothe (Author), Dieter Schollmeyer (Author), Christian Miculka (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Praziquantel (PZQ) is the drug compound of choice in the control and treatment of schistosomiasis. PZQ is administered as a racemate, i. e. 1ratio1 mixture of enantiomers. The schistosomicidal activity arises from one PZQ-enantiomer, whereas the other enantiomer does not contribute to th...