Development of foaming vaginal tablets with clotrimazole. Part I. Optimization of the formulation using design of experiments approach
Objectives. The aim of this study was to optimize the formulation of certain immediate release foaming vaginal tablets, with fast vaginal disintegration (part I), fallowing their time stability (part II). Material and methods. Modde optimizing software and a Box-Bhenken experimental design was used...
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Amaltea Medical Publishing House,
2020-06-01T00:00:00Z.
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