Degradation rates and products of fluticasone propionate in alkaline solutions

• Главные авторы: Tadakazu Tokumura (Автор), Naoko Yoshida (Автор), Kanami Mori-Yasumoto (Автор), Osamu Shirota (Автор), Takuro Kurita (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2017-10-01T00:00:00Z.
• Предметы: article
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The apparent degradation rate constant of fluticasone propionate (FLT) in 0.1 M NaOH:methanol=1:1 at 37 °C was previously reported to be 0.169±0.003 h−1, and four degradation products (products 1-4) were observed in the solution. The aims of the present study were to assess the degradation rates of...