In Vivo Investigation of (2-Hydroxypropyl)-β-cyclodextrin-Based Formulation of Spironolactone in Aqueous Solution for Paediatric Use

• Main Authors: Antonio Lopalco (Author), Annachiara Manni (Author), Alexander Keeley (Author), Shozeb Haider (Author), Wenliang Li (Author), Angela Lopedota (Author), Cosimo Damiano Altomare (Author), Nunzio Denora (Author), Catherine Tuleu (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Spironolactone (SPL), a potent anti-aldosterone steroidal drug used to treat several diseases in paediatric patients (e.g., hypertension, primary aldosteronism, Bartter's syndrome, and congestive heart failure), is not available in child-friendly dosage forms, and spironolactone liquids have be...