Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles

• Asıl Yazarlar: Livio Racané (Yazar), Valentina Rep (Yazar), Sandra Kraljević Pavelić (Yazar), Petra Grbčić (Yazar), Iva Zonjić (Yazar), Marijana Radić Stojković (Yazar), Martin C. Taylor (Yazar), John M. Kelly (Yazar), Silvana Raić-Malić (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

A series of 6-amidinobenzothiazoles, linked via phenoxymethylene or directly to the 1,2,3-triazole ring with a p-substituted phenyl or benzyl moiety, were synthesised and evaluated in vitro against four human tumour cell lines and the protozoan parasite Trypanosoma brucei. The influence of the type...