Discriminative Dissolution Method Using the Open-Loop Configuration of the USP IV Apparatus to Compare Dissolution Profiles of Metoprolol Tartrate Immediate-Release Tablets: Use of Kinetic Parameters

• Main Authors: Bruno Solis-Cruz (Author), Daniel Hernandez-Patlan (Author), Elvia A. Morales Hipólito (Author), Guillermo Tellez-Isaias (Author), Alejandro Alcántara Pineda (Author), Raquel López-Arellano (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The use of the USP IV apparatus (flow-through cell) has gained acceptance in recent years due to its versatility and ability to discriminate due to its hydrodynamic conditions. Therefore, the objective of the present study was to develop a discriminative dissolution method in the USP IV apparatus us...