Ratiometric delivery of doxorubicin and berberine by liposome enables superior therapeutic index than DoxilⓇ

• Main Authors: Ruoshi Zhang (Author), Yingxi Zhang (Author), Yue Zhang (Author), Xin Wang (Author), Xuanming Gao (Author), Yuyan Liu (Author), Xuanbo Zhang (Author), Zhonggui He (Author), Dun Wang (Author), Yongjun Wang (Author)
• Format: Book
• Published: Elsevier, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although the appearance of Doxil alleviated the cardiotoxicity of DOX, the progression-free survival of patients was not prolonged compared with traditional medication regimens, and side effects such as hand-foot syndrome has occurred. In order to solve this dilemma, we have designed a novel co-deli...