Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells

• Main Authors: Jon Voutila (Author), Pål Sætrom (Author), Paul Mintz (Author), Guihua Sun (Author), Jessica Alluin (Author), John J Rossi (Author), Nagy A Habib (Author), Noriyuki Kasahara (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells. Using bioinformatics analysis and functional screening, we screened short-activating RNA (saRNA) oligonucleotides designed to target the promoter re...