Assessing Lipid Nanoparticle Protein Corona Formation and Cytocompatibility

• Main Authors: Rand Abdulrahman (Author), Huda Ibrahem (Author), Amna Mahmood (Author), Kevin Edward Treacher (Author), Robin Bruno Capomaccio (Author), Catherine Vasey (Author), Yvonne Perrie (Author), Zahra Rattray (Author)
• Format: Book
• Published: University of Huddersfield Press, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipid nanoparticles(LNPs) represent an emerging new modality for mRNA delivery. Following administration and interaction with blood constituents, LNPs form a corona complex consisting of proteins adsorbed on the surface altering their stability, biological identity, and fate. Cytocompatibility of th...