The efficacy of HDAC inhibitors in neoplasm treatment

• Main Authors: Dominika Psiuk (Author), Agata Rocka (Author), Klaudia Żak (Author), Żaklina Tomczyk (Author), Agata Filip (Author)
• Formato: Livro
• Publicado em: Kazimierz Wielki University, 2020-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Introduction and purpose: Histone Deacetylases (HDACs) are associated with epigenetic regulation of gene expression. They are responsible of adequate action of not only histone proteins, but also crucial cell cycle proteins, such as p53, NF‐κB or alpha tubulin. Recent studies have shown the connecti...