The effect of angiotensin 1-7 and losartan on renal ischemic/reperfusion injury in male rats

• Main Authors: Tahereh Safari (Author), Mohamad Reza Shahraki (Author), Saideh Miri (Author), Nasime Mirakzehi Bakhshani (Author), Abbass Ali Niazi (Author), Gholam Reza Komeili (Author), Hossain Bagheri (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ischemia/reperfusion (I/R) is a major cause of acute kidney injury. Several studies have shown that renin angiotensin (Ang) system and activation of Ang II type 1 receptor (AT1) are involved in various forms of kidney diseases. Likewise, Ang 1-7 as a physiologic antagonist of AT1 and losartan could...