Competitive α-glucosidase inhibitors, dihydrobenzoxanthones, from the barks of Artocarpus elasticus

• Main Authors: Janar Jenis (Author), Aizhamal Baiseitova (Author), Sang Hwa Yoon (Author), Chanin Park (Author), Jeong Yoon Kim (Author), Zuo Peng Li (Author), Keun Woo Lee (Author), Ki Hun Park (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to search the α-glucosidase inhibitors from the barks part of Artocarpus elasticus. The responsible compounds for α-glucosidase inhibition were found out as dihydrobenzoxanthones (1-4) and alkylated flavones (5-6). All compounds showed a significant enzyme inhibition toward α-glucos...