Association between time in therapeutic range of tacrolimus blood concentration and acute rejection within the first three months after lung transplantation

• Main Authors: Yoshiki Katada (Author), Shunsaku Nakagawa (Author), Kotaro Itohara (Author), Takuya Suzuki (Author), Ryota Kato (Author), Hiroki Endo (Author), Mitsuhiro Sugimoto (Author), Atsushi Yonezawa (Author), Takayuki Nakagawa (Author), Akihiro Ohsumi (Author), Daisuke Nakajima (Author), Hiroshi Date (Author), Tomohiro Terada (Author)
• Format: Book
• Published: BMC, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Tacrolimus is a key drug in immunosuppressive therapy following lung transplantation. The blood tacrolimus levels are likely to fluctuate in the early postoperative period, and failure to maintain the tacrolimus trough level in target ranges is a risk factor for rejection. Howeve...