Role of microRNAs and DNA methyltransferases in transmitting induced genomic instability between cell generations

• Main Authors: Katriina eHuumonen (Author), Merja eKorkalainen (Author), Matti eViluksela (Author), Tapani eLahtinen (Author), Jonne eNaarala (Author), Jukka eJuutilainen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is limited understanding of how radiation or chemicals induce genomic instability, and how the instability is epigenetically transmitted to the progeny of exposed cells or organisms. Here we measured the expression of microRNAs (miRNAs) and DNA methyltransferases (DNMTs) in murine embryonal fi...