Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies

• Main Authors: Andrew Dippel (Author), Austin Gallegos (Author), Vineela Aleti (Author), Arnita Barnes (Author), Xiaoru Chen (Author), Elizabeth Christian (Author), Jared Delmar (Author), Qun Du (Author), Reza Esfandiary (Author), Erika Farmer (Author), Andrew Garcia (Author), Qing Li (Author), Jia Lin (Author), Weiyi Liu (Author), LeeAnn Machiesky (Author), Neil Mody (Author), Arun Parupudi (Author), Meagan Prophet (Author), Keith Rickert (Author), Kim Rosenthal (Author), Song Ren (Author), Harini Shandilya (Author), Reena Varkey (Author), Kevin Wons (Author), Yuling Wu (Author), Yueh-Ming Loo (Author), Mark T. Esser (Author), Nicole L. Kallewaard (Author), Sarav Rajan (Author), Melissa Damschroder (Author), Weichen Xu (Author), Gilad Kaplan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTTo combat the COVID-19 pandemic, potential therapies have been developed and moved into clinical trials at an unprecedented pace. Some of the most promising therapies are neutralizing antibodies against SARS-CoV-2. In order to maximize the therapeutic effectiveness of such neutralizing antib...