Cell volume restriction by mercury chloride reduces M1-like inflammatory response of bone marrow-derived macrophages

• Main Authors: Yen-Chieh Chuang (Author), Shu-Yu Wu (Author), Yu-Chuan Huang (Author), Chung-Kan Peng (Author), Shih-En Tang (Author), Kun-Lun Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dysregulation of macrophages in the pro-inflammatory (M1) and anti-inflammatory (M2) sub-phenotypes is a crucial element in several inflammation-related diseases and injuries. We investigated the role of aquaporin (AQP) in macrophage polarization using AQP pan-inhibitor mercury chloride (HgCl2). Lip...