Antitumor and apoptotic effects of bergaptol are mediated via mitochondrial death pathway and cell cycle arrest in human breast carcinoma cells

• Main Authors: Zhi-Cheng Ge (Author), Xiang Qu (Author), He-Fen Yu (Author), Hui-Ming Zhang (Author), Zi-Han Wang (Author), Zhong-Tao Zhang (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the present research work was to investigate the anti-cancer and apoptotic effects of bergaptol in human breast cancer cells (MCF-7). The effects on cell cycle arrest and caspase activation were evaluated. MTT assay was used to evaluate the effect of the compound on cell viability. Cellul...