Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention

• Main Authors: Yi Zhu (Author), Na Li (Author), Mingyang Huang (Author), Xi Chen (Author), Yu A. An (Author), Jianping Li (Author), Shangang Zhao (Author), Jan-Bernd Funcke (Author), Jianhong Cao (Author), Zhenyan He (Author), Qingzhang Zhu (Author), Zhuzhen Zhang (Author), Zhao V. Wang (Author), Lin Xu (Author), Kevin W. Williams (Author), Chien Li (Author), Kevin Grove (Author), Philipp E. Scherer (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adipose tissue is a promising target for treating obesity and metabolic diseases. However, pharmacological agents usually fail to effectively engage adipocytes due to their extraordinarily large size and insufficient vascularization, especially in obese subjects. We have previously shown that during...