Azilsartan Suppresses Osteoclastogenesis and Ameliorates Ovariectomy-Induced Osteoporosis by Inhibiting Reactive Oxygen Species Production and Activating Nrf2 Signaling

• Main Authors: Bin Pan (Author), Lin Zheng (Author), Jiawei Fang (Author), Ye Lin (Author), Hehuan Lai (Author), Jiawei Gao (Author), Wenzheng Pan (Author), Yejin Zhang (Author), Kainan Ni (Author), Chao Lou (Author), Dengwei He (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoporosis is characterized by a decrease in bone mass and destruction of the bone microarchitecture, and it commonly occurs in postmenopausal women and the elderly. Overactivation of osteoclasts caused by the inflammatory response or oxidative stress leads to osteoporosis. An increasing number of...